Program members can track the progress of their program’s clinical and molecular data submission and download analysis files from the Program Dashboard.
When a program member logs in to the ARGO Data Platform, and navigates to the Program Services area in the top menu, they will land on the program dashboard. If a member belongs to multiple programs, each program has its own dashboard and submission sections.
Program Overview: Statistics and Progress
The first half of the Program Dashboard highlights important metrics of progress and statistics to display a program's completion status of molecular and clinical data against the number of donors that have been committed for submission to ARGO.
Program progress is summarized within the following dashboard "cards":
The top card aggregates important program statistics:
- The number of Registered donors, with a progress bar showing the goal of % Registered/Committed donors
- The percentage of registered donors with complete clinical data. Once the minimum amount of required clinical data has been submitted for a donor, they are considered clinically complete.
- The percentage of donors with submitted raw reads for a matched tumour/normal pair. Once a donor has both a tumour and matched normal raw sequencing data pair submitted through Song, they will be counted towards this percentage.
A donor must be clinically complete before any of their molecular analysis files are released to the program members.
A donor must also have data for at least one T/N pair before submitted before molecular processing will begin.
Donor Release Summary
Coming Soon: The status bar in this card shows how many program donors have fully released files (dark blue bar), partially released files (light blue bar) and no released files (white bar) out of the total number of donors committed to ARGO by the program.
Program Workspace Status
The Program Workspace consists of the sample registration as well as the clinical submission areas.
All program members share the same workspace, so members are encouraged to communicate with each other when a sample registration or clinical submission is in progress.
Sample Registration Progress: this progress bar will show if there are uploaded samples that haven’t been registered yet. A blank status bar means this area is free to register samples.
Clinical Submission Progress: this progress bar will show if a clinical submission currently has uploaded files or if it has been validated and is ready for sign off. If a submission is signed off without any updates to previously submitted data, this progress bar will become blank again, signifying that this area is free to submit clinical data. If the progress bar is in “pending approval” state, this means the clinical submission area has been locked and is under review by the DCC. Once the DCC approves the clinical data updates, the progress bar will become blank and the clinical submission area is free for a new submission.
Clinical Completeness Data Summary
This line graph tracks how many donors have complete clinical data over time.
- Check out Clinical Data Validation Rules for more information on how clinical completion is calculated.
- As soon as a donor's clinical data is completed, this chart will update in real-time.
Molecular Data Summary
This line graph compares how many donors have been processed through the DNA-Seq Pipeline (Raw Read Submission, Alignment, Sanger VC...) over time.
- Use the legend to toggle different pipeline steps on/off to check progress of different processing steps.
- This chart is updated in real-time. While the data may show that a donor has been processed in the molecular summary chart, the donor files may not yet be released to the program if that donor is lacking complete clinical data.
Donor Data Summary
This table is a detailed summary of the clinical data status and DNA-Seq pipeline status for each registered donor in the program. It also shows which donors have files that have been released to the public via the File Repository.
Using the button above the table, a program member can download all clinical data that has been submitted for the program donors. The download will be in the same file format that was submitted through the sample registration and clinical submission sections.
The table is sorted by default on the last updated date, so a program member will always see the donors with the most recent activity first. The table can be sorted by another column by clicking on any other column header.
Released Files Status
Each donor has a star that denotes if they have fully released files, partially released files or no released files. In order to have released files, the embargo period must be over and the donor must have 100% core completeness as well as some molecular analysis completed.
Clinical Data Status
The table shows the percentage of core clinical fields that have been submitted for a donor.
- If no clinical data is submitted, this column is blank.
- If some clinical data is submitted, then the percentage towards completion is shown.
- Core completion must be 100% (showing ) for any analysis files to be released to the program members for download.
- See how this percentage is calculated
A donor's registered tumour and normal sample count as well as submitted raw reads count are also tracked within this table.
- In the samples column, a 0N (normal) or 0T (tumour) will be highlighted in red for any missing tumour/normal pair (each donor must have at least one normal and one tumour sample registered).
- Once raw samples are submitted through Song, those counts will appear in the raw reads column. Similarly, the raw reads normal and tumour count will be highlighted in red for any instance where no sample files have been submitted.
The donor summary table also shows where each donor sample is at in the DNA-Seq Pipeline. In the pipeline columns, a progress bar will appear if the donor has any samples processing through these workflow types.
- A green section with a number will show how many donor samples have completed that workflow.
- An orange section with a number will show how many donor samples are currently processing that workflow.
- A red section with a number will show how many donor samples have stopped processing because of a workflow error.
- Hovering over these sections will show the specific Submitter Sample IDs for each workflow status.
The last updated table column indicates when this donor was last updated with new data submission or molecular analysis.
ICGC ARGO member programs will have privileged access to data from other members of the Consortium based on their level of Membership. Data access is tiered and aimed not to disadvantage Members or Associate Member Data producers, with a framework that encourages data sharing, yet provides data generators with sufficient time to perform analyses:
Up to 12 months from completion of standardized analyses: Access to Program submitting data only
- 12 months: Access to Full Members
- 18 months: Access to Associate Members
- 24 months: Accessible by external parties
If you are logged in, the File Repository will show an additional facet to sort on your priviledged access to pre-release data. Pre-release data is sorted into 4 categories based on the ARGO Data Management policy.
- My Program Access: These files are visible to Program Members only.
- Full Member Access: These files are visible to both the Program Members that submitted the data and to other ARGO Program Members that are part of Full Member programs.
- Associate Member Access: These files are visible to both the Program Members that submitted the data and to other ARGO Program Members that are part of Associate Member programs.
- Released to the Public: These files are publicly visible to any user that visits the ARGO Data Platform file Repository. If the file is
controlled acccessDACO permissions are required to download the file. If the file is
openaccess, it can be downloaded anonymously.